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Omevir 20


Omeprazole BP

PRESENTATION

Omevir 20 Capsule: Each capsule contains Omeprazole BP 20 mg as enteric coated Pellets.

INDICATION

Omevir is indicated for the treatment of benign gastric and duodenal ulcers  including   those  complicating   NSAID  therapy,  erosive oesophagitis and for disorders associated with hyper secretion of gastric acid, such as the Zollinger-Ellison syndrome.

DOSAGE & ADMINISTRATION

Benign gastric and duodenal ulcers including those complicating NSAID therapy:20 mg once daily for 4 weeks in duodenal ulceration 8 weeks in gastric ulceration. In severe cases the dose may be increased to 40 mg daily; long term use is not recommended.

Healing of reflux esophagitis: 20 mg daily for 4 weeks, followed by further 4-8 weeks if not fully healed; 40 mg daily has been given for 8 weeks in reflux esophagitis refractory to other treatment; may be continued at 20 mg daily.

Zollinger-Ellison syndrome: Initially 60 mg once daily; usual range 20-120 mg daily (above 80 mg in 2 divided doses). Larger doses of up to 180 mg daily in divided doses may be used or as prescribed by the physicians.

CONTRAINDICATION

There are no known contraindications to the use of Omeprazole.

USE IN PREGNANCY & LACTATION

Avoid in pregnancy unless there is no safer alternative. Breast feeding should be discontinued if the use of Omeprazole is considered essential.

SIDE EFFECTS

Omeprazole is well tolerated. Nausea, diarrhea, paresthesia, dizziness and headache have been stated to be generally mild and transient and not requiring a reduction in dosage.

PRECAUTIONS & WARNINGS

Symptomatic  response to  therapy with  Omeprazole  does  not preclude the presence of gastric malignancy. When gastric ulcer is suspected, the possibility of malignancy should be excluded before treatment with Omeprazole is instituted as treatment may alleviate symptoms and delay diagnosis.

DRUG INTERACTIONS

Omeprazole can delay the elimination of diazepam, phenytoin and warfarin. Reduction of warfarin or phenytoin dose may be necessary when Omeprazole is added to the treatment, There is no evidence of interaction with theophylline, propranolol or antacids.

PHARMACEUTICAL PRECAUTIONS

Store in a cool and dry place, protected from light and moisture. Keep out of the reach of children.

PACKAGE QUANTITIES

Omevir 20 Capsule: Each box contains 10 X 10’s capsules in Alu-Alu blister pack.

 

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